The high-throughput DNA sequencing system GenoLab M adopts the surface fluorescent sequencing technique (SURF-seq) based on chip amplification to identify the opytical signals of bases. Notably, with the unique “rolling mode” of GenoLab M, the second flow cell can be loaded and start working while the first flow cell is still running, and the two chips can produce data of different reads or sequencing types as required by the client, so as to shorten the waiting time, widen the scope of application, and bring unprecedented user experience.